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crispr-primer-design

🔌Plugin

wayneliuq/claude-skills

Installation

Add marketplace in Claude Code:

$/plugin marketplace add wayneliuq/claude-skills

Step 2. Install plugin:

$/plugin install crispr-primer-design@wayneliuq

What it does

Design and genome-verify PCR + nested Sanger primers to validate CRISPR-Cas9 cutting at a gRNA locus (ICE / TIDE / amplicon-NGS)

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Part of

wayneliuq/claude-skills

AddedAug 17, 2026

View on GitHub Back to Plugins

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first-principles🔌Plugin

Coding discipline as seven independent outcome-based gates rather than a workflow: scope-gate, build-gate, cut-gate (47-shape bloat catalog tiered by blast radius, plus a two-question test-value rule; the one gate that edits, logging every finding before it touches anything), done-gate, bug-gate (18-shape bug catalog, findings tiered proven / traced / suspected), ship-gate, watch-gate — plus adversarial-delegation for running a gate over a worker you review rather than trust, over a shared canon of five first principles and a six-rule security spine. Each gate produces a verdict with evidence and admits gaps explicitly.

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wayneliuq/claude-skills🏪Marketplace

Personal Claude Code skills and plugins